2006-01-01から1年間の記事一覧

Kim H, Shimojo S, O’doherty JPIs Avoiding an Aversive Outcome Rewarding? Neural Substrates of Avoidance Learning in the Human Brain.PLoS Biol. 2006 Jul 4;4(8):e233

2006 PLoS Biol John P. O’Doherty human fMRI reward aversive OFC

PLoS Biology - Is Avoiding an Aversive Outcome Rewarding? Neural Substrates of Avoidance Learning in the Human Brain リスク回避は報酬になりうるか？ ＊ 引用文献がふるいな！てゆうかリスクじたいが報酬になるひとのばあいはどうなるんだろう？

Bunzeck N, Duzel EAbsolute coding of stimulus novelty in the human substantia nigra/VTANeuron. 2006 Aug 3;51(3):369-79

DA novelty salience hippocampus SN VTA human fMRI

Neuron - Absolute Coding of Stimulus Novelty in the Human Substantia Nigra/VTA Neuron - The Lure of the Unknownコメント; "The lure of the unknown." Pure novelty spurs the brainニュース記事 女房と畳はなんとやら、美人は3日で慣れるけれどブス…

O’Reilly RCBiologically based computational models of high-level cognition.Science. 2006 Oct 6;314(5796):91-4.

Randall C. O’Reilly PFC basal ganglia DA

Biologically Based Computational Models of High-Level Cognition -- O’Reilly 314 (5796): 91 -- Science生物学に基づいた高次認知の計算モデル in silicoやon paperのはなしでなく、じっさいの生物学的研究からの知見にもとづいた計算モデルによって、人…

Sae Unoki, Yukihisa Matsumoto and Makoto MizunamiRoles of octopaminergic and dopaminergic neurons in mediating reward and punishment signals in insect visual learningEuropean Journal of Neuroscience Volume 24 Page 2031 - October 2006 doi:10.1111/j.1460-95

2006 Eur J Neurosci DA reward aversive insect

Wiley InterScience :: Session Cookies 昆虫ではオクトパミン（OA）が報酬にもとづくポジティブな学習に、ドーパミン（DA）が嫌悪刺激にもとづくネガティブな学習にかかわっているっていう。コオロギにたいして視覚刺激による条件付け課題をやってる。OA受…

Ravel S, Richmond BJDopamine neuronal responses in monkeys performing visually cued reward schedules.Eur J Neurosci. 2006 Jul;24(1):277-90.

Sabrina Ravel Barry J. Richmond DA monkey single-unit salience

Wiley InterScience :: Session Cookies しかしSalienceのはなしです。シダラリッチモンドので有名な報酬スケジュール課題(visually cued reward schedule task)をやってるサルのドーパミンニューロンを記録、多くがスケジュールの最初または最後のトライア…

Morris G, Nevet A, Arkadir D, Vaadia E, Bergman HMidbrain dopamine neurons encode decisions for future action.Nat Neurosci. 2006 Aug;9(8):1057-63. Epub 2006 Jul 23.

Genela Morris Hagai Bergman monkey DA single unit RL reward

Midbrain dopamine neurons encode decisions for future action - Nature Neuroscience Choice values - Nature Neuroscience 中脳ドーパミンニューロンは将来の行動をコードする…ふたつのターゲット（条件刺激）が提示されたときのドーパミンニューロンの…

De Martino B, Kumaran D, Seymour B, Dolan RJFrames, biases, and rational decision-making in the human brain.Science. 2006 Aug 4;313(5787):684-7.

human fMRI decision-making emotion neuroeconomics Amygdala ACC OFC vmPFC

Frames, Biases, and Rational Decision-Making in the Human Brain -- De Martino et al. 313 (5787): 684 -- Science NEUROSCIENCE: The Emotional Brain Weighs Its Options -- Miller 313 (5787): 600b -- Science 田辺三菱製薬 | お知らせヒトの脳にお…

Daw ND, O’Doherty JP, Dayan P, Seymour B, Dolan RJCortical substrates for exploratory decisions in humansNature. 2006 Jun 15;441(7095):876-9

Daw Dayan Dolan TD RL decision-making human fMRI FP IPS vmPFC exploration uncertainty

Page not found : Nature Publishing Group認知：ヒトの情報探索の意思決定にかかわる皮質領域 たえず変化しつづける環境では、たまには冒険を…つまり、知識と経験から導かれる最適（利益を最大化する）な行動でないけれども、ひょっとしたらすごく得するか…

Zangen A, Solinas M, Ikemoto S, Goldberg SR, Wise RA. Two brain sites for cannabinoid reward. J Neurosci. 2006 May 3;26(18):4901-7.

Two Brain Sites for Cannabinoid Reward -- Zangen et al. 26 (18): 4901 -- Journal of Neuroscience

Tobler PN, Fiorillo CD, Schultz WAdaptive coding of reward value by dopamine neurons.Science. 2005 Mar 11;307(5715):1642-5

2006 Science Philippe N. Tobler Christopher D. Fiorillo Wolfram Schultz DA monkey reward

Discrete Coding of Reward Probability and Uncertainty by Dopamine Neurons -- Fiorillo et al. 299 (5614): 1898 -- Science 視覚刺激にたいしては90ms(90-180ms; monkey A), 130ms(110-240ms; monkey B)。Rew delivery、Norewの視覚刺激にたいしては200…

Fiorillo CD, Tobler PN, Schultz WDiscrete coding of reward probability and uncertainty by dopamine neurons.Science. 2003 Mar 21;299(5614):1898-902.

Christopher D. Fiorillo Philippe N. Tobler Wolfram Schultz DA reward

Discrete Coding of Reward Probability and Uncertainty by Dopamine Neurons -- Fiorillo et al. 299 (5614): 1898 -- Science イベント前1秒間と比較。最大応答の平均時刻を中心に、応答の60％が含まれるようにウィンドウを設定。CS_onにたいして90ms(90-…

Morris G, Nevet A, Arkadir D, Vaadia E, Bergman HMidbrain dopamine neurons encode decisions for future action.Nat Neurosci. 2006 Aug;9(8):1057-63. Epub 2006 Jul 23.

Genela Morris Hagai Bergman monkey DA single unit RL TD reward

Midbrain dopamine neurons encode decisions for future action - Nature Neuroscience Low frequency(<15Hz), long duration(>1.5ms) and polyphasic spikes, and a firing elevation in background single- and multi-unit activity in response to unexp…

Nakahara H, Itoh H, Kawagoe R, Takikawa Y, Hikosaka ODopamine Neurons Can Represent Context-Dependent Prediction ErrorNeuron, Vol 41, 269-280, 22 January 2004

中原裕之 彦坂興秀 DA monkey reward RL TD

Neuron - Dopamine Neurons Can Represent Context-Dependent Prediction Error MRでニグラの位置決め、irregular and tonic firing with broad spike potentials…シュルツロモ（1987）にもとづいて。記録終了後ヒストロジー、A9およびA8のSNcからの記録を確…

Schultz WResponses of midbrain dopamine neurons to behavioral trigger stimuli in the monkey.J Neurophysiol 56(5): 1439–1461, 1986.

DA monkey Schultz

Responses of midbrain dopamine neurons to behavioral trigger stimuli in the monkey -- Schultz 56 (5): 1439 -- Journal of Neurophysiology

Schultz W, Romo RResponses of nigrostriatal dopamine neurons to high-intensity somatosensory stimulation in the anesthetized monkey.J Neurophysiol. 1987 Jan;57(1):201-17.

DA Schultz Romo

Responses of nigrostriatal dopamine neurons to high-intensity somatosensory stimulation in the anesthetized monkey -- Schultz and Romo 57 (1): 201 -- Journal of Neurophysiology ・low-frequency discharges of long duration ( 1.4 - 5.0 ms )

O’Brien C. Rat study sheds light on cocaine craving. Science. 1996 Mar 15;271(5255):1499.

Neurobiology: Rat Study Sheds Light on Cocaine Craving -- O’Brien 271 (5255): 1499 -- Science 上のコメント。

Self DW, Barnhart WJ, Lehman DA, Nestler EJ. Opposite modulation of cocaine-seeking behavior by D1- and D2-like dopamine receptor agonists. Science. 1996 Mar 15;271(5255):1586-9.

DA drug reward D1 D2 rat Self Nestler

Opposite Modulation of Cocaine-Seeking Behavior by D1- and D2-Like Dopamine Receptor Agonists -- Self et al. 271 (5255): 1586 -- Science コカインシーキング(priming effect)をD2受容体が促進し、D1受容体が抑制する。

Eyny YS, Horvitz JC. Opposing roles of D1 and D2 receptors in appetitive conditioning. J Neurosci. 2003 Mar 1;23(5):1584-7.

DA reward D1 D2 rat Eyny Horvitz

Opposing Roles of D1 and D2 Receptors in Appetitive Conditioning -- Eyny and Horvitz 23 (5): 1584 -- Journal of Neuroscience 長期増強はD1受容体ブロックで抑制され、D2受容体ブロックで促進されるっていうけど、じゃあD1拮抗薬のSCH23390やD2拮抗薬…

Wang Z, Aragona BJ. Neurochemical regulation of pair bonding in male prairie voles. Physiol Behav. 2004 Nov 15;83(2):319-28.

DA

ScienceDirect - Physiology & Behavior : Neurochemical regulation of pair bonding in male prairie voles プレーリーハタネズミにおけるつがい形成にたいするバソプレッシン、オキシトシン、ドーパミンの役割。D1受容体とD2受容体では、細胞内シグナル伝…

Young LJ, Wang Z. The neurobiology of pair bonding. Nat Neurosci. 2004 Oct;7(10):1048-54.

pair-bonding Young Wang

Page not found : Nature Publishing Group pair-bondingレビュー。よんでなかった…！

Lim MM, Wang Z, Olazabal DE, Ren X, Terwilliger EF, Young LJ. Enhanced partner preference in a promiscuous species by manipulating the expression of a single gene. Nature. 2004 Jun 17;429(6993):754-7.

Access : Enhanced partner preference in a promiscuous species by manipulating the expression of a single gene : Nature ページを表示できません : Nature Asia-Pacific Page not found : Nature Publishing Group 一夫一妻制の遺伝子 乱婚制のサンガ…

Reynolds SM, Berridge KC. Glutamate motivational ensembles in nucleus accumbens: rostrocaudal shell gradients of fear and feeding. Eur J Neurosci. 2003 May;17(10):2187-200.

NAcc glutamate motivation rat Reynolds Berridge

Wiley InterScience :: Session Cookies ラット側坐核shellにAMPA型グルタミン酸受容体阻害剤であるDNQXを注入すると、吻側では食欲増進効果、尾側では恐怖にたいする動機づけが強まって、それらの効果はrostro-caudal方向にきれいなgradientをもって顕れて…

Edwards S, Self DW. Monogamy: dopamine ties the knot. Nat Neurosci. 2006 Jan;9(1):7-8.

Monogamy: dopamine ties the knot - Nature Neuroscience コメント。

Aragona BJ, Liu Y, Yu YJ, Curtis JT, Detwiler JM, Insel TR, Wang ZNucleus accumbens dopamine differentially mediates the formation and maintenance of monogamous pair bonds. Nat Neurosci. 2006 Jan;9(1):133-9. Epub 2005 Dec 4.

DA reward D1 D2 NAcc

Nucleus accumbens dopamine differentially mediates the formation and maintenance of monogamous pair bonds - Nature Neuroscience 動物がつがいをつくって、きっちり子孫を残すことは進化のうえで重要なんよ。人間みたいに（ほとんどが）単婚制で、子…

Hammock EA, Young LJ. Microsatellite instability generates diversity in brain and sociobehavioral traits. Science. 2005 Jun 10;308(5728):1630-4.

Microsatellite Instability Generates Diversity in Brain and Sociobehavioral Traits -- Hammock and Young 308 (5728): 1630 -- Science サイエンスにも。プレーリーハタネズミのV1aR遺伝子周辺領域（上流の転写調節因子にあたる繰り返し配列）の水銀灯D…

Aragona BJ, Liu Y, Curtis JT, Stephan FK, Wang Z. A critical role for nucleus accumbens dopamine in partner-preference formation in male prairie voles. J Neurosci. 2003 Apr 15;23(8):3483-90.

Aragona Wang DA NAcc

A Critical Role for Nucleus Accumbens Dopamine in Partner-Preference Formation in Male Prairie Voles -- Aragona et al. 23 (8): 3483 -- Journal of Neuroscience いっこまえの仕事。これもプレーリーハタネズミで、partner preferenceは側坐核shell…

Adams RB Jr, Gordon HL, Baird AA, Ambady N, Kleck RE. Effects of gaze on amygdala sensitivity to anger and fear faces. Science. 2003 Jun 6;300(5625):1536.

amygdala fMRI Adams Kleck

Science/AAAS | Science Magazine: Sign In 1ページ（サプリメントも）！扁桃体が「threat-related ambiguity」、んーと脅迫感に関連したあいまいさ？の処理に関わってんじゃないかっていう。それまで怒ってる顔を見せたときにも、怖がってる顔を見せたとき…

Rustichini A. Neuroscience. Emotion and reason in making decisions. Science. 2005 Dec 9;310(5754):1624-5.

Rustichini

NEUROSCIENCE: Emotion and Reason in Making Decisions -- Rustichini 310 (5754): 1624 -- Science 上のレビュー。

Hsu M, Bhatt M, Adolphs R, Tranel D, Camerer CF. Neural systems responding to degrees of uncertainty in human decision-making. Science. 2005 Dec 9;310(5754):1680-3.

neuroeconomics gambling uncertainty risk ambiguity human fMRI OFC Amygdala striatum Hsu Camerer

Neural Systems Responding to Degrees of Uncertainty in Human Decision-Making -- Hsu et al. 310 (5754): 1680 -- Science Uncertainty - Wikipedia, the free encyclopedia Risk - Wikipedia, the free encyclopedia Ambiguity - Wikipedia, the free e…

Yu AJ, Dayan P. Uncertainty, neuromodulation, and attention. Neuron. 2005 May 19;46(4):681-92.

uncertainty attention ACh Norepinephrine Yu Dayan

Neuron - Uncertainty, Neuromodulation, and Attention Neuron - Technical Difficulties Page Expected uncertaintyとUnexpected uncertainty。riskとambiguity？いぜんセミナーで紹介しておきながら、ぜんぜんおもいださんかった… もういちどタスクを思い…